Prostaglandin F<SUB>2α</SUB>注射によるめん羊の発情同期化

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  • Estrus synchronization of the ewe by subcutaneous injections of prostaglandin F<SUB>2α</SUB>

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The effects of prostaglandin F2α (PGF2α) on the estrous cycle were investigated in the ewe. The conception rate in the following estrus were also examined.<BR>When a total amount of 10 or 15 mg of PGF2α was injected intravenously at an interval of 24 hours on Days 7 and 8 of the estrous cycle (Day 0 refers to the first day of estrus), no significant shortning of the estrous cycle were observed in two ewes. However, when a total amount of 10 mg PGF2α was injected intramuscularly on the same days, the estrous cycle shortened to 9.5 days and 13.5 days in two ewes. All, except one, of seven ewes, that were given a total amount of 6-27 mg PGF2α by subcutaneous (s. c.) injections on the morning and evening of Day 7, and the morning of Day 8, came into estrus within 12 days after the treatment. Their estrous cycles shortened to 8-10 days. The luteolytic action of PGF2α seemed to be most effective when injected s. c. at three times on successive two days.<BR>In 12 of 16 ewes that were given a total amount of 1217 mg PGF2α at three times by s. c. injections on successive two days between Day 3 and Day 13 of the estrous cycle, estrus occurred within 12 days after the treatment. Three out of the remaining 4 ewes showing delayed estrus were young ewes aged 7 months.<BR>Nineteen ewes were served by natural mating at the first estrus, which occurred 12 days after the treatment, and 9 (47.4%) of them conceived.<BR>The results indicated that PGF2α could be applied to the synchronization of estrus in the ewe.

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