Function and Role of Indigenous Bacteria

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  • 常在菌の働き, 役割

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Characteristic bacterial species inhabit on or in the human body including the skin, mouth, pharynx, stomach, intestine, vagina, urethra, and make up indigenous bacterial flora. Equilibria exist not only between the indigenous flora and the host, but also between the different species within the flora. Many of indigenous bacteria are potential pathogens, while many non-pathogenic species have a similarly localized distribution. If the equilibra are disturbed by certain factors, the potential pathogens may become involved such socalled “opportunistic infections” as bacteremia, pneumonia, lung abscess, lung gangrene, peritonitis, cholecystitis, cholangitis, liver abscess, diarrhea, enteritis, stomatitis, tonsillitis, brain abscess, meningitis, pyelitis, cystitis, vaginitis, puerperal feber, endocarditis, tympanitis, conjunctivitis, soft tissue abscess, etc. Disturbances of equiblila are seen in such factors as administration of antibacterial agents or steroid homons, surgical operations, stresses, diabetes, overwork, aging, etc. Moreover, the intestinal flora possess a variety of enzymes that perform the extremely varied types of metabolism in the intestine, and influence host's health and diseases, including nutrition, physiologic function, drug efficacy, carcinogenesis, aging as well as the host's immunological responses.

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