発熱と関節痛で急性発症した家族発生サルコイドーシスの１例

DOI
  • 駒瀬 裕子
    聖マリアンナ医科大学横浜市西部病院呼吸器内科
  • 山口 裕礼
    聖マリアンナ医科大学横浜市西部病院呼吸器内科
  • 池原 瑞樹
    聖マリアンナ医科大学横浜市西部病院呼吸器内科
  • 山本 崇人
    聖マリアンナ医科大学横浜市西部病院呼吸器内科
  • 森田 あかね
    聖マリアンナ医科大学横浜市西部病院呼吸器内科

書誌事項

タイトル別名
  • A Case of Familial Sarcoidosis with Acute Onset of Fever and Arthralgia

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説明

A 22-year-old male was admitted to our hospital with high fever and arthralgia. He had a family history of sarcoidosis of the mother's sister and mother's cousin. He visited his family doctor complaining of continuing fever for one month and multiple arthralgia. His initial chest X-ray and CT showed bilateral hilar and mediastinal lymphadenopathy. Chest CT showed no pulmonary abnormality. Pathology of lung specimen obtained by trans-bronchial lung biopsy showed noncaseating epithelioid cell granuloma, suggesting sarcoidosis. No lymphocyte monoclonality was seen in this specimen. His symptom disappeared only with non-corticosteroid anti-inflammatory agents, and hilar and mediastinal lymphadenopathy on chest X-ray disappeared after one year follow up. Human leukocyte antigen (HLA) typing of this patient and his aunt showed A31 as the same locus.

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