土佐褐毛和種にみられた低セルロプラスミン血症

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タイトル別名
  • Low Serum Ceruloplasmin in Cattle
  • トサ カツモウワシュ ニ ミラレタ テイ セルロプラスミン ケッショウ エイブ

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抄録

Low ceruloplasmin (Cp) activity has been observed in two paternal half-sib cows of Japanese Brown breed. The plasma of the cows showed no Cp band on starchgel with o-dianisidine or p-phenylenediamine used as a substrate. The oxidase activity of the low Cp cow was one fifth that of normal cows with p-phenylenediamine used as a substrate. In the other survey, one cow and her offspring showed the same result, but the other cow and her relatives showed normal Cp activity. This result indicates that the low Cp is not primarily due to their sire, but to environmental or seasonal effects. The plasma of the low Cp cows contained small amounts of ceruloplasmin when measured by a single radial immunodiffusion test using anti-rabbit serum against HoloCp. Purified Apo-Cp had extremely poor antigenicity against Holo-Cp antiserum by immuno-electrophoresis and double immunodiffusion tests. Since total Cp content (Apo plus Holo) was almost similar level in both low Cp and normal plasma, it seems likely that a conversion process from Apo-form to Holo-form in the liver was disturbed.

収録刊行物

  • 日本畜産学会報

    日本畜産学会報 56 (8), 658-666, 1985

    公益社団法人 日本畜産学会

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