書誌事項
- タイトル別名
-
- No Observed Adverse Effect Levels of Phthalate Esters on Reproductive and Developmental Toxicity, the Differences with Age and Species in Testicular Toxicity, and Tolerable Daily Intake of DEHP
- フタルサン エステル ノ セイショク ハッセイ ムドクセイリョウ セイソウ ドクセイ ノ シュウレイサ シュサ オヨビ DEHP ノ 1ニチ タイヨウセッシュリョウ
この論文をさがす
抄録
It is well known that some species of phthalate esters have reproductive and developmental toxicity, monoesters being active metabolites. In June 2000, the Japanese Government established a tolerable daily intake (TDI) for di(2-ethylhexyl) phthalate (DEHP) based on data for testicular and reproductive toxicity because of the report that certain cooked foods had been relatively high contaminated, caused by the use of polyvinyl chloride gloves containing DEHP in the final stage of food packing. In the present paper, first of all, no observed adverse effect levels (NOAELs) or lowest observed adverse effect levels (LOAELs) of various kinds of phthalate esters in terms of reproductive and developmental toxicity endpoints, and the differences with age and species in testicular toxicity are examined and summarized. Then the rationale for establishing a TDI for DEHP and the exposure problem are discussed. This article also includes new information from a draft of the Toxicological Profile for DEHP published in September 2000 by the US Agency for Toxic Substances and Disease Registry, and assessment reports made available in October 2000 from the Center for the Evaluation of Risks to Human Reproduction, US National Toxicology Program.
収録刊行物
-
- 日本食品化学学会誌
-
日本食品化学学会誌 8 (1), 1-10, 2001
日本食品化学学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390001205195348352
-
- NII論文ID
- 110007367211
-
- NII書誌ID
- AA11666400
-
- ISSN
- 21896445
- 13412094
-
- NDL書誌ID
- 5768807
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- NDL
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可