Crystal Structure of Ketotifen Fumarate

DOI Web Site 参考文献2件
  • AKIMOTO Toshio
    Basic Medical Science and Molecular Medicine, Tokai University School of Medicine
  • HIRAYAMA Noriaki
    Basic Medical Science and Molecular Medicine, Tokai University School of Medicine

抄録

The crystal structure of ketotifen fumarate was determined. The crystal belongs to space group P1 and there are two molecules in an asymmetric unit. The cell dimensions are a = 10.0901(6), b = 11.7760(7), c = 18.8200(7)Å, α = 74.054(2), β = 81.034(3) and γ = 88.4315(7)°. The final R value is 0.068. The two crystallographically independent ketotifen molecules adopt very similar structures. Their tricyclic systems take a butterfly-shape structure.

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