[Updated on Apr. 18] Integration of CiNii Articles into CiNii Research

Investigation of the Possible Mechanism Underlying Acquired Childhood Alexia with Agraphia in a Reading Aloud Task

  • Kozuka Junko
    Graduate School of Comprehensive Human Sciences, University of Tsukuba. Children's Development and Human Health Department, Saitama Children's Medical Center LD/Dyslexia Centre
  • Uno Akira
    Graduate School of Comprehensive Human Sciences, University of Tsukuba. LD/Dyslexia Centre
  • Sanbai Ami
    Macquarie University JSPS Postdoctoral Fellow for Research Abroad

Bibliographic Information

Other Title
  • 小児の失読失書 1 例における音読の障害機序に関する検討
  • —In the Framework of the Dual-route Cascaded Model
  • ─二重経路モデルを適用して─

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We report a 10-year-old, right-handed boy who showed alexia and agraphia. His impairments were caused by cerebral infarctions due to Moyamoya disease. Magnetic resonance imaging (MRI) revealed lesions in the left temporal and left occipital lobes. We investigated the possible mechanism underlying his alexia in the framework of the dual-route cascaded model. The boy manifested cognitive visual impairment in the form of deficits in both detection of visual features of a character and identification of a character from its visual features, collectively resulting in a deficit in activating both the lexical and non-lexical reading routes. Additionally, in the non-lexical route, character-to-sound conversion is thought to be severely impaired, because the boy could not read all Kana characters and he showed-2SD below average on the Kanji nonword reading task. In the lexical route, the orthographic input lexicon is assumed to be dysfunctional, due to low performance, below-1.5SD, on the lexical decision task with Kanji word sti-muli. Access to the semantic system and the semantic system itself are assumed to be active normally, based on the results for normal ability on the Standardized Comprehension Test of Abstract Words and the naming task in the Standard Language Test of Aphasia.


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