Frontal lobe and memory

DOI Web Site 21 References Open Access

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  • 前頭葉と記憶
  • —A review from neurological standpoint—
  • —神経内科の立場から—

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This review summarized roles of the frontal lobe in encoding and retrieval of episodic memory, access to semantic memory, and working memory on the basis of lesion and neuroimaging studies. Left prefrontal cortex is more activated in successful encoding of episodic memory, whereas bilateral frontal lobes contribute to retrieval of episodic memory. Novel episodes are encoded through the network involving anterior cingulate cortex, orbitofrontal cortex, and temporal lobe. Memory traces for semantic memory are stored in the temporal lobe, but the left inferior prefrontal cortex is essential for access to semantic memory. Working memory plays a central role in frontal executive function. Middle and inferior frontal gyri are activated in working memory task in association with the activation of the parietal lobe.

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