Diencephalic amnesia

DOI Web Site 23 References Open Access
  • Nishio Yoshiyuki
    Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University School of Medicine.
  • Mori Etsuro
    Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University School of Medicine.

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Other Title
  • 間脳性健忘

Description

The neural circuit that arises from the hippocamupus via the fornix, the mammillary body, the mammillothalamic tract and the anterior thalamic nuclei and projects back to the hippocampus, known as the Papez or Delay-Brion circuit, has long been considered to play a critical role in memory. In addition, the significance of the neuroanatomical network among the rhinal / parahippocampal cortices, the mediodorsal nucleus of the thalamus and the prefrontal cortices has been recently recognized. Most researchers have placed a greater emphasis on the importance of the Papez circuit disruption in diencephalic amnesia. However, close inspection of neuropsychological literature and our recent study on anterior thalamic infarction in the tuberothalamic artery territory suggest that there are multiple circuit disruptions in cases of diencephalic amnesia.

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