Mode of Growth Inhibitory Activity and Metabolism of Imazosulfuron in Excised Roots of Plants
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- SHIMIZU Naofumi
- Agricultural Research Laboratories, Agro Division, Takeda Chemical Industries, Ltd.
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- SAKAMOTO Junko
- Pharmaceutical Research Laboratories, Pharmaceutical Research Division, Takeda Chemical Industries, Ltd.
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- KAMIZONO Hiroshi
- T. N. Technos Co., Ltd.
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- OHTA Kazunari
- Agricultural Research Laboratories, Agro Division, Takeda Chemical Industries, Ltd.
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- TASHIRO Shigeki
- Agricultural Research Laboratories, Agro Division, Takeda Chemical Industries, Ltd.
Bibliographic Information
- Other Title
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- イマゾスルフロンの植物切断根における生長抑制作用機構および代謝
- Mode of Growth Inhibitory Activity and
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Description
Growth inhibition activity of imazosulfuron, 1-(2-chloroimidazo [1, 2-a] pyridin-3-ylsulfonyl)-3-(4, 6-dimethoxypyrimidin-2-yl)urea, against excised pea and soybean roots was investigated. Fifty percents growth inhibition concentrations of imazosulfuron (I50) against pea and soybean roots were 17.6 and 54.2ppb, respectively. When the excised pea roots were incubated in the culture medium containing 25ppb of imazosulfuron and 1mM of either branched-chain amino acids or intermediates of their biosynthetic pathways, the growth inhibition activity of excised roots was alleviated by the combination of isoleucine and valine or α-ketoisovalerate and α-keto-β-methyl-n-valerate. These findings suggest that imazosulfuron exhibits inhibition of acetolactate synthase which catalyses the biosynthetic pathways of branchedchain amino acids. Metabolic fate of imazosulfuron in excised pea roots was studied using the 14C-labeled compounds. imazosulfuron was predominantly demethylated to afford a monodemethyl derivative (HMS) in the roots, and hydrolytically cleaved at the sulfonylurea bond to give a sulfonamide (IPSN) and an aminopyrimidine (ADPM) in the culture medium. Since HMS did not inhibit the growth of excised roots, metabolic fate of imazosulfuron is involved in a selectivity between plants.
Journal
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- Journal of Pesticide Science
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Journal of Pesticide Science 21 (3), 287-292, 1996
Pesticide Science Society of Japan
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Details 詳細情報について
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- CRID
- 1390001205210771968
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- NII Article ID
- 110001712928
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- NII Book ID
- AN00196227
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- ISSN
- 03851559
- 13490923
- 1348589X
- http://id.crossref.org/issn/1348589X
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- NDL BIB ID
- 4021979
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- NDL-Digital
- CiNii Articles
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- Abstract License Flag
- Disallowed