Bendiocarb Metabolism in Adults and Larvae of the Southern Corn Rootworm, <i>Diabrotica undecimpunctata howardi</i>

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  • <i>Diabrotica undecimpunctata howardi</i> (ハムシの一種) の成虫および幼虫における bendiocarb の代謝
  • Diabrotica undecimpunctata howardi(ハムシの一種)の成虫および幼虫におけるbendiocarbの代謝〔英文〕
  • Diabrotica undecimpunctata howardi ハムシ

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Abstract

The toxicity and metabolism of bendiocarb were compared between adults and larvae of southern corn rootworm (SCR), Diabrotica undecimpunctata howardi BARBER. The 48-hr topical LD50 values of bendiocarb to SCR adults and larvae were 1.3 and 9.1μg/g, respectively. Bendiocarb was approximately seven times less toxic to SCR larvae than to adults. In the metabolism studies, SCR adults and larvae were analyzed at specific time intervals after treatment with 14C-bendiocarb at sublethal 1/10 LD50 dosage level. The major metabolites from bendiocarb were bendiocarb phenol and conjugated compounds for SCR adults and larvae, respectively. The proposed major metabolic pathways of bendiocarb in SCR were hydrolysis of the carbamate ester bond to yield bendiocarb phenol and the subsequent conjugation of bendiocarb phenol. The ratio of applied dose to internal toxic compound was similar for both adults and larvae. Therefore, the amount of internal toxic compound, affected by the rates of penetration, metabolism, and excretion, was not a determining factor in the selective toxicity of bendiocarb between SCR adults and larvae.

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