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A Randomized Human Study on the Safety and Effectiveness of Powdered Food of <i>Agaricus blazei Murill</i>
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- UEBABA Kazuo
- Faculty of Health Science, Teikyo Heisei University
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- KYO Hoko
- Department of Complementary and Alternative Medicine Clinical R&D Kanazawa University Graduate School of Medical Science
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- SUZUKI Nobutaka
- Department of Complementary and Alternative Medicine Clinical R&D Kanazawa University Graduate School of Medical Science
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- URATA Teturo
- Urata Clinic, Hospy Medical Association
Bibliographic Information
- Other Title
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- アガリクス<i> (Agaricus blazei Murill ) </i>粉末食品の安全性と有効性に関するランダム化ヒト試験
- アガリクス(Agaricus blazei Murill)粉末食品の安全性と有効性に関するランダム化ヒト試験
- アガリクス(Agaricus blazei Murill)フンマツ ショクヒン ノ アンゼンセイ ト ユウコウセイ ニ カンスル ランダムカ ヒト シケン
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Description
Safety and effectiveness of powered food made from Agaricus blazei Murill was evaluated by a randomized human study. 45 healthy subjects were divided into 3 groups in sequence: control, 1 pack and 3 packs/day-administered groups. Each group had 15 persons. They had each packs for 28 days, and followed, in every two weeks, by the evaluation with CTCAE v3.0, QOL (SF36-v2), and biochemical examinations including liver/lung/kidney function, insulin resistance and NK activity and high-sensitivity CRP. None of them had adverse events nor biochemical/lung abnormal examinations. 1 and 3 packs-administered groups improved their QOL, high-sensitivity CRP and NK activity in a dose-dependent manner. These results ascertained safety, and effectiveness of the powdered food made from Agaricus blazei Murill against presymptomatic disorders including metabolic syndrome.
Journal
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- Japanese Journal of Complementary and Alternative Medicine
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Japanese Journal of Complementary and Alternative Medicine 12 (2), 95-101, 2015
The Japanese Society for Complementary and Alternative Medicine
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Details 詳細情報について
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- CRID
- 1390001205218343168
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- NII Article ID
- 130005117186
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- NII Book ID
- AA12095429
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- ISSN
- 13487930
- 13487922
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- NDL BIB ID
- 026940129
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL Search
- Crossref
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed