Safety of Excessive Intake of <i>Ashitaba</i> Green Juice in Normal and Borderline Mildly Diabetic Subjects

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  • 健常人および境界域糖尿病者に対する明日葉青汁の過剰摂取時の安全性評価
  • ケンジョウジン オヨビ キョウカイイキ トウニョウビョウシャ ニ タイスル アス ヨウ セイジュウ ノ カジョウ セッシュジ ノ アンゼンセイ ヒョウカ

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Objective: “Ashitaba” (Angelica keiskei) is a traditional vegetable peculiar to Japan. Ashitaba contains vitamins, dietary fiber and polyphenols such as chalcones abundantly. We previously reported anti-diabetic action of Ashitaba in an animal model as well as in diabetics. In this study, we evaluated the safety of Ashitaba green juice in healthy and borderline mildly diabetic subjects.<br> Methods: Japanese adult subjects (n = 24) ingested Ashitaba green juice (31.5 g granulated powder) for 4 weeks. For evaluation of safety, blood chemistry analysis, hematological analysis and urinalysis were conducted.<br> Result: On excessive ingestion of Ashitaba green juice for 4 weeks, there were no adverse clinical changes in blood analysis and urinary analysis and no serious symptom was observed.<br> Conclusion: These results indicate that excessive ingestion of Ashitaba green juice is safe in healthy and borderline mildly diabetic subjects.<br>

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