A Mathematical Model Integrating Musculoskeletal and Cardiovascular Systems

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Other Title
  • 運動器系・循環器系の統合的数理モデルの構築

Abstract

<p>The purpose of this study is to construct a mathematical model which can reproduce the variation of blood pressure and cardiovascular dynamics during physical exercise, and also to clarify that mechanism by a computer simulation. Pedaling exercise was assumed as an objective human movement, and a musculoskeletal model reproducing pedaling motion with given rotation speed was constructed. A mathematical model integrating the musculoskeletal and cardiovascular systems was established by referring to previous cardiovascular models with a continuous time system and by adding cooperation mechanisms between both systems such as characteristics of the central command and the peripheral chemoreceptor. Additionally, a simple model which can calculate the flow of arterial blood from blood pressure was embedded in the integration model so as to consider oxygen supply corresponding with blood pressure variation. Simulation results such as blood pressure variability and cardiac cycle wave closely agreed with characters of the experimental results. The simulation result also pointed out importance of the shift in the baroreceptor set point.</p>

Journal

  • Biomechanisms

    Biomechanisms 18 (0), 57-68, 2006

    Society of Biomechanisms

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