Protective Effect of Polyphenol on Cytotoxicity of 24S-Hydroxycholesterol on the Brain-Derived Cells
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- HASEGAWA Eri
- Department of Bio-Analytical Chemistry, Niigata University of Pharmacy and Applied Life Sciences
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- NAKAGAWA Saori
- Department of Bio-Analytical Chemistry, Niigata University of Pharmacy and Applied Life Sciences
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- TAKAHASHI Kaori
- Department of Bio-Analytical Chemistry, Niigata University of Pharmacy and Applied Life Sciences
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- YAMATO Susumu
- Department of Bio-Analytical Chemistry, Niigata University of Pharmacy and Applied Life Sciences
Bibliographic Information
- Other Title
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- 24S-ヒドロキシコレステロールの細胞毒性に対するポリフェノールの保護効果
- 24S‐ヒドロキシコレステロールの細胞毒性に対するポリフェノールの保護効果
- 24S ‐ ヒドロキシコレステロール ノ サイボウ ドクセイ ニ タイスル ポリフェノール ノ ホゴ コウカ
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Abstract
The protection to the cytotoxicity of 24S-hydroxycholesterol on the brain-derived cells should be useful as a new therapy of Alzheimer’s disease. In this study, we have revealed neuroprotective effect of polyphenol, especially (−)-epigallocatechin-3-gallate and (−)-epicatechin gallate on cytotoxicity of 24S-hydroxycholesterol. These results suggest the possibility of a new complementary therapy for Alzheimer’s disease.<br>
Journal
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- Japanese Journal of Complementary and Alternative Medicine
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Japanese Journal of Complementary and Alternative Medicine 9 (1), 65-68, 2012
The Japanese Society for Complementary and Alternative Medicine
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Keywords
Details 詳細情報について
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- CRID
- 1390001205220781696
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- NII Article ID
- 130001923988
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- NII Book ID
- AA12095429
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- ISSN
- 13487930
- 13487922
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- NDL BIB ID
- 023685722
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed
