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- Hironaka Naoyuki
- Shimojo Implicit Brain Function Project, Japan Science and Technology Agency, ERATO NTT Communication Science Laboratories
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- Takano Yuji
- Shimojo Implicit Brain Function Project, Japan Science and Technology Agency, ERATO NTT Communication Science Laboratories
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- Takahashi Nobuaki
- Shimojo Implicit Brain Function Project, Japan Science and Technology Agency, ERATO NTT Communication Science Laboratories
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- Tanaka Tomoko
- Shimojo Implicit Brain Function Project, Japan Science and Technology Agency, ERATO National Center of Neurology and Psychiatry
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- Michio Itasaka
- Shimojo Implicit Brain Function Project, Japan Science and Technology Agency, ERATO Graduate School of Senshu University
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- Koizumi Miwako
- Shimojo Implicit Brain Function Project, Japan Science and Technology Agency, ERATO Ochannomizu University Graduate School
Bibliographic Information
- Other Title
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- 報酬探索の神経機構と快情動
- ホウシュウ タンサク ノ シンケイ キコウ ト カイ ジョウドウ
Search this article
Abstract
It is difficult to study “hedonic” or “pleasant” emotion with nonhuman animals. We have to deal with objectively observable behavior. In this regard, we investigated neural mechanisms of reward seeking. In a series of experiments, we have shown that(1)the endogenous nociceptin modulates preference for high fat diet,(2)the theta rhythm in the hippocampus possibly relates to prediction of reward,(3) dopamine receptors in the hippocampus increased along with the formation of reward memory, and (4)dopamine receptors in the amygdala play an important role in the behavioral expression of preference. These results indicate the significance of learning and memory in reward seeking. Although reward seeking is an essential biological function for survival, the very same system is also responsible for the pathological states such as addiction and dependence. We must further study and clarify both natural and aberrant aspects of reward seeking. The revealed nature of which will then sheds light on the structure and function of “hedonic” or “pleasant” emotion.
Journal
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- Japanese Journal of Cognitive Neuroscience
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Japanese Journal of Cognitive Neuroscience 13 (1), 96-102, 2011
Japanese Society of Cognitive Neuroscience
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Details 詳細情報について
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- CRID
- 1390001205224267648
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- NII Article ID
- 130006895654
- 40018888704
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- NII Book ID
- AA11408788
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- ISSN
- 1884510X
- 13444298
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- NDL BIB ID
- 11150325
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed