Influence of Intrathoracic Pressure at Defecation on Cardiovascular System

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  • 排便時における怒責圧が循環系に及ぼす影響
  • ハイベンジ ニ オケル ド セキアツ ガ ジュンカンケイ ニ オヨボス エイキョウ

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Abstract

Background : The aim of this study was to compare the influence of intrathoracic (IT) pressure at defecation on cardiovascular system in sitting and supine positions<br/>　Methods : Twenty one healthy volunteers (age 32.7 ± 10.1 years, 12 men) consented to participate in this study. They followed the protocols to perform IT pressures at 10, 20, and 30 mmHg in supine and sitting positions for each 15 sec in the environmentally controlled room chamber (27℃,50%rh). All signals of BP and HR were digitally sampled.<br/>　Results : In sitting and supine positions, the BP and HR showed the large change as the IT pressure increased. These reaction showed not only during IT pressure load but also after it release. At the IT pressure of 30 mmHg, the Δ SBP of phase Ⅰ to Ⅱ a was larger in sitting 41.43 ± 13.30 mmHg, than supine 26.86 ± 19.59 mmHg (p＜0.001). The IT pressure of 10 and 20 mmHg were the same. There was a large significant (p<0.01) increase in Δ HR of phase Ⅰ to Ⅱ a and Ⅲ to Ⅳ for sitting.<br/>　Conclusions : The high IT pressure at the defecation might give the great influence to cardiovascular system. Under the same IT pressure, the sitting position may cause great influence to hemodynamics.

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