New Method for Inhibition of Peristalsis During Transnasal Endoscopy Using Lemon Juice

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  • 経鼻内視鏡におけるレモン果汁を用いた新しい蠕動抑制法の検討
  • ケイ ビ ナイシキョウ ニ オケル レモン カジュウ オ モチイタ アタラシイゼンドウ ヨクセイホウ ノ ケントウ

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Abstract

Objective: A randomized comparative study was performed to examine the effectiveness and safety of a method developed to inhibit peristalsis during transnasal endoscopy using lemon juice.<br>Methods: The subjects were 80 patients who underwent transnasal endoscopy at our hospital from June to August 2011. They were randomly divided into 2 groups using the envelope method. During the examination, 15 ml of lemon juice (Group A) or distilled water (Group B) was injected into the duodenum. Peristalsis in the gastric antrum was scored from 1 (no peristalsis) to 4 (severe peristalsis) before and after injection. Blood pressure, heart rate, and SpO2 were measured before, immediately after, and 3 minutes after injection.<br>Results: The percentage of patients with no peristalsis after injection was significantly higher in Group A (39.5%) than in Group B (0%) (p<0.00001). The mean peristalsis scores before and after injection were 2.34 and 1.79, respectively, in Group A, and 2.47 and 2.64, respectively, in Group B. There was no significant difference in scores between the groups before injection. The score in Group A significantly decreased after injection (p<0.01) and was significantly lower than that in Group B (p<0.0001). Blood pressure, heart rate, and SpO2 did not differ significantly between the groups.<br>Conclusion: These results show that use of lemon juice to inhibit peristalsis during transnasal endoscopy is effective and safe. This method is widely applicable and should contribute to improving the accuracy of transnasal endoscopy.

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