Screening for Early Glaucoma using Frequency Doubling Technology in General Health Check-up

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  • 正常眼圧緑内障早期発見を目的としたFrequency Doubling Technology視野計の予防医療導入の検討
  • セイジョウガンアツ リョクナイショウ ソウキ ハッケン オ モクテキ ト シタ Frequency Doubling Technology シヤケイ ノ ヨボウ イリョウ ドウニュウ ノ ケントウ

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Objective: Normal tension glaucoma(NTG) is more prevalent in Japan than in other countries. It has been reported that glaucoma affects 5.78% of Japanese people over the age of 40 years and NTG comprises two-thirds of Japanese glaucoma cases. Glaucoma is the main cause of blindness in Japan because patients with NTG are usually asymptomatic in the early stage. As fundus photography performed during general health check-up seems to be inadequate for detecting NTG, our objective was to evaluate the usefulness of frequency doubling technology (FDT) perimetry in screening for NTG.<br>Methods: Two hundred thirty-eight employees (88 males, 150 females) of our hospital underwent FDT perimetry, fundus photography with a non-mydriatic camera and non-contact tonometry. Their ages ranged from 22 to 72 years (mean, 43.0 years).<br>Results: FDT detected visual field abnormalities (VFA) in 30 subjects. Among them, 10 subjects underwent ophthalmologic diagnosis and 7 (70.0%) were diagnosed with glaucoma {6 with NTG [4 with early NTG who did not have VFA using Humphrey Field Analyzer, and 2 almost free from fundus abnormalities (FA)]}. On the other hand, fundus photography detected FA in 12 subjects who did not have VFA in FDT perimetry. Among them, 8 subjects underwent ophthalmologic diagnosis and only 1 subject (12.5%) was suspected of having NTG.<br>Conclusions: FDT may be useful in mass screening for early detection of NTG but it would be even more useful to use FDT together with fundus photography.

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