Investigations on the Status of <i>Helicobacter pylori</i> (HP) Infection Status and Endoscopic Findings for ABC Classification Group A Subjects

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  • 胃がんリスク評価ABC分類のA群における上部消化管内視鏡所見と<i>Helicobacter pylori</i>感染の状態の検討
  • 胃がんリスク評価ABC分類のA群における上部消化管内視鏡所見とHelicobacter pylori感染の状態の検討
  • イガン リスク ヒョウカ ABC ブンルイ ノ Aグン ニ オケル ジョウブ ショウカカン ナイシキョウ ショケン ト Helicobacter pylori カンセン ノ ジョウタイ ノ ケントウ

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Objective: We compared the findings of esophagogastroduodenoscopy (EGD) with the result of the gastric cancer risk evaluation according to the ABC classification and examined the Helicobacter pylori (HP) infection status.<br>Methods: The subjects were 345 persons who were classified as Group A by the ABC classification and underwent EGD. They were examined in consideration of scores in the Kimura-Takemoto and Kyoto classifications.<br>Results: Based on EGD findings for the 345 subjects in Group A, atrophy was present in 7.5% by the Kimura-Takemoto classification and HP infection in 7.2% based on the endoscopic image score for gastric cancer risk of the Kyoto classification of gastritis atrophy. From the endoscopic findings of 307 subjects with serum HP antibody <3 U/mL, the rates for the HP infection group based on the endoscopic findings score for gastric cancer risk of the Kyoto classification of gastritis was 2.0% and the rate of atrophy by the Kimura-Takemoto classification was also 2.0%. There was a significant difference in serum PGII levels between the HP infection group and HP non-infection group according to the gastritis score of the Kyoto classification.<br>Conclusion: Presence of gastric HP infection was suggested by the endoscopic findings score for gastric cancer risk of the Kyoto classification and Kimura-Takemoto classification even for those classified as group A by the ABC classification. HP infection should not only be diagnosed based on the ABC classification but also with reference to serum PGII levels, and in combination with endoscopic diagnosis the gastric cancer risk should also be assessed.

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