Creations of biological Pacemaker
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- Narazaki Genta
- Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
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- Yamashita Jun K.
- Center for iPS Cell Research and Application (CiRA), Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto, Japan
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Abstract
The heart is one of the most important targets of regenerative medicine. The pacemaker, which controls the rate of beating, is also a target of regeneration. Until today, various researches have been aiming at generating biological pacemakers, but there are only a few reports about detailed analyses of candidates of cells for a really functional pacemaker. Recently, we reported novel induction methods of spontaneous beating cardiomyocytes from mouse embryonic stem (ES) cells, and detailed analysis of ion channel dynamics during their differentiation. This review briefly overviews up to date researches about biological pacemaker and our results achieved recently.
Journal
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- Inflammation and Regeneration
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Inflammation and Regeneration 29 (2), 123-127, 2009
The Japanese Society of Inflammation and Regeneration
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Details 詳細情報について
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- CRID
- 1390001205257287168
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- NII Article ID
- 10024797269
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- NII Book ID
- AA11508953
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- ISSN
- 18808190
- 18809693
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- NDL BIB ID
- 10248646
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed