等容性収縮期における左心室壁の変形解析：心筋線維の配向性が壁変形に与える影響

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タイトル別名
  • Finite Deformation Analysis of Left Ventricular Wall in Isovolumetric Contraction Period: Effects of Myocardial Fiber Orientation on Wall Deformation
  • トウ ヨウセイ シュウシュクキ ニ オケル サシンシツヘキ ノ ヘンケイ カイセキ : シンキン センイ ノ ハイコウセイ ガ カベ ヘンケイ ニ アタエル エイキョウ

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説明

The aim of this study was to elucidate the effects of myocardial fiber orientation on the deformation of the left ventricular (LV) wall. An LV wall model was constructed by modeling the myocardial fiber structure as an anisotropic hyperelastic material. The shapes of the endocardium and epicardium were assumed to be two spheroids. LV wall deformation by constriction of the myocardial fibers was simulated for three fiber orientations:the myocardial fiber was oriented parallel to the short-axis plane (Case 1) ; the angle between the myocardial fiber and the short-axis plane varied linearly from +π/3 in the endocardium to -π/3 in the epicardium (Case 2) ; and the myocardial fiber was uniformly oriented at an angle of -π/3 with respect to the short-axis plane (Case 3). The results showed that the LV wall deformation was governed by the interaction among the constriction of fibers, the wall deformation as a continuum body, and the geometric constrains of the LV anatomy. Comparing the results of three cases revealed that the helical structure of fibers contributes to cause a twisting motion and efficient contraction of the LV wall, which produces a heterogeneous distribution of the deformation rates in the LV wall.

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  • 生体医工学

    生体医工学 54 (1), 28-37, 2016

    公益社団法人 日本生体医工学会

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