A comparative study between the levels of gastric mucosal atrophy determined by radiography screening and ABC classification: A higher incidence of gastric mucosal atrophy was observed even in the elderly classified into Group A

  • SATO Tsunenobu
    Comprehensive Medical Checkup Center, Chiba Foundation for Health Promotion and Disease Prevention Department of Gastroenterology, Chiba Chuo Medical Center
  • YAMAGUCHI Kazuya
    Comprehensive Medical Checkup Center, Chiba Foundation for Health Promotion and Disease Prevention
  • SUGIYAMA Sonomi
    Comprehensive Medical Checkup Center, Chiba Foundation for Health Promotion and Disease Prevention
  • AKABANE Asana
    Comprehensive Medical Checkup Center, Chiba Foundation for Health Promotion and Disease Prevention
  • MITSUHASHI Kanae
    Comprehensive Medical Checkup Center, Chiba Foundation for Health Promotion and Disease Prevention
  • HAYASHI Manabu
    Comprehensive Medical Checkup Center, Chiba Foundation for Health Promotion and Disease Prevention

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Other Title
  • 対策型胃X線検診での萎縮度評価とABC分類の年齢階級別対比─高齢者ではA群でも萎縮進行例が多い─
  • 対策型胃X線検診での萎縮度評価とABC分類の年齢階級別対比 : 高齢者ではA群でも萎縮進行例が多い
  • タイサクガタ イ Xセン ケンシン デ ノ イシュクド ヒョウカ ト ABC ブンルイ ノ ネンレイ カイキュウ ベツ タイヒ : コウレイシャ デワ Aグン デモ イシュク シンコウレイ ガ オオイ

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Abstract

Backgrounds: Although the patients classified into Group A in ABC classification are regarded as being at low risk of gastric cancer, it raises the concern that the incidence ratio of gastric mucosal atrophy is higher than expected in the elderly. <BR>Materials and Methods: We compared, according to age, ABC classification and the levels of gastric mucosal atrophy determined by radiography screening. 1168 participants of population-based screening for gastric cancer conducted at Village C in Chiba Prefecture in March 2013 were enrolled. Participants with a history of Helicobacter pylori (HP) eradication, under treatment for gastric disease, gastroesophageal reflux disease or gastric resection were excluded by interview form. Blood was collected from participants on the day X-ray examination was performed after obtaining written informed consent.<BR>Results: In the elderly group (70 years or older), the rate with gastric mucosal atrophy was 40-50%, even though the participants were classified into Group A. Evaluation utilizing HP antibody (less than 3 U/ml) or Pepsinogen method was inappropriate to exclude gastric mucosal atrophy. <BR>Conclusions: A higher incidence of gastric atrophy was observed in the elderly who were originally classified into Group A by ABC classification. Additional diagnosis by imaging is required to exclude severe atrophic gastritis.

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