Review of the Rates of Cases of Colorectal Cancer with Submucosal or Deeper Invasion Discovered in Individual Screening which Required Close Examination

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  • SUDA Takeo
    Committee for Colorectal Cancer Screening of Omiya Medical Association
  • NAKANO Makoto
    Committee for Colorectal Cancer Screening of Omiya Medical Association
  • HASUMI Tadahiko
    Committee for Colorectal Cancer Screening of Omiya Medical Association
  • MATSUZAWA Yoshikazu
    Committee for Colorectal Cancer Screening of Omiya Medical Association
  • TABATA Ikuo
    Committee for Colorectal Cancer Screening of Omiya Medical Association
  • TAKAGI Shunji
    Committee for Colorectal Cancer Screening of Omiya Medical Association
  • MATSUMOTO Masahiko
    Committee for Colorectal Cancer Screening of Omiya Medical Association

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Other Title
  • 大腸がん個別検診で発見されたsm以深癌からみた要精検率の検討
  • ダイチョウ ガン コベツ ケンシン デ ハッケンサレタ smイシン ガン カラ ミタ ヨウセイケンリツ ノ ケントウ

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The cases of colorectal cancer discovered in individual screening performed in the Omiya district of Saitama City were divided by assay values determined from fecal occult blood tests into 5 groups: a)110-199, b)200-299, c)300-399 ,d)400-499, and e)500∼ng/ml , and the rates of cases which required close examination were reviewed to explore the possibility of failing to discover colorectal cancer distributed in each group according to the cut-off assay values.<BR>Of the 1,159 cases of colorectal cancer discovered, 447 cases were with sm or deeper invasion, and 54 cases (12.1%) were in group a) and 317 cases (70.9%) were in group e). There was a higher number (rate) of cases discovered with higher assay values, but more than a few cases were also discovered in group a). In these circumstances, if the cut-off value of 110 ng/ml is changed to 200 ng/ml, the rate of cases requiring close examination would be reduced from 9.02% to 4.71%, but 54 cases (12.1%) of cancer with sm or deeper invasion (of which 24 cases were with mp or deeper invasion) in group a) would become false-negative and thus be missed.<BR>While the individuals who seek colorectal cancer screening have exceeded 35,000 in number in recent years, there has been no significant change in the number who require close examination, and in fact the rate of cases prescribed to require close examination has been showing a tendency to decrease gradually.<BR>In order to optimize the rate of cases that require close examination, it seemed important to perform screening using the present cut-off values and analyze the cases of cancer discovered while making an effort to increase the number of individuals who seek screening and the rate of those who seek close examination.

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