Paraneoplastic Syndrome with Sensory Polyneuropathy : A Report on Rehabilitation in Two Cases

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  • KAWADA Rieko
    Department of Rehabilitation Medicine, Kawasaki Medical School
  • AOYAGI Yoichiro
    Department of Rehabilitation Medicine, Kawasaki Medical School
  • HIRAOKA Takashi
    Department of Rehabilitation Medicine, Kawasaki Medical School
  • YAMANAKA Takashi
    Department of Rehabilitation, Takemoto Hospital
  • KUNIYASU Katsushi
    Department of Rehabilitation, Faculty of Health Science and Technology, Kawasaki University of Medical Welfare
  • TSUBAHARA Akio
    Department of Rehabilitation Medicine, Kawasaki Medical School

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Other Title
  • 四肢感覚障害を呈した傍腫瘍性神経症侯群の 2 症例に対するリハビリテーションの経験
  • 症例報告 四肢感覚障害を呈した傍腫瘍性神経症候群の2症例に対するリハビリテーションの経験
  • ショウレイ ホウコク シシ カンカク ショウガイ オ テイシタ ボウ シュヨウセイ シンケイ ショウコウグン ノ 2 ショウレイ ニ タイスル リハビリテーション ノ ケイケン

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Abstract

We report two cases of paraneoplastic syndrome with sensory polyneuropathy. Case one showed numbness of the upper and lower extremities before a diagnosis of small cell carcinoma was made. Case two showed the same symptoms coincidentally with a recurrence of ovarian cancer. In both cases, Romberg's sign was positive, ataxic gait was noted, and the patient's skill movement was disturbed. Sensory nerve action potentials were not evoked in any of the nerves. Compound muscle action potential and motor conduction velocity were at the lower limits of normal. The neurological abnormalities did not resolve in spite of medical treatments. In these two cases, the loss of sensory neurons due to a lesion of the dorsal root ganglia was suggested. The loss of sensory feedback might lead to muscle weakness and fatigue, so they tend to be disused. For long-term rehabilitation management in these two cases, we suggested a regular exercise program to prevent muscle weakness.

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