Integrated Chemical Processの開発による合成プロセスの自動化

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タイトル別名
  • Automation of Organic Synthesis on the Basis of Integrated Chemical Process.
  • Integrated Chemical Process ノ カイハツ ニ ヨル ゴウセイ プロセス ノ ジドウカ

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The automation of multi-step chemical processes has been realized. A new concept for one-pot processes has been advanced which enables integration of various types of reactions involving carbon-carbon bond formations and functional group modifications. In the meantime, an automated synthesizer to accommodate such one-pot processes has been devised. This machine allows us to reproduce usual bench work : treatment of air-sensitive materials, control of temperature from -78°C to 100°C within ± 0.1°C accuracy, and successive addition of reagents. Several examples which were successfully conducted on the machine are described.

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