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Effect of continuous positive airway pressure on gastroesophageal reflux in sleep apnea syndrome
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- Sato Hideo
- Division of Respiratory Medicine, Nagaoka Chuo General Hospital
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- Iwashima Akira
- Division of Respiratory Medicine, Nagaoka Chuo General Hospital
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- Kawabe Syotetsu
- Division of Respiratory Medicine, Nagaoka Chuo General Hospital
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- Nakayama Hideaki
- Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
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- Yoshizawa Hirohisa
- Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
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- Gejyo Fumitake
- Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
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- Suzuki Eiichi
- Division of General Medicine, Niigata University Medical and Dental Hospital
Bibliographic Information
- Other Title
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- 睡眠時無呼吸症候群の胃食道逆流症合併とCPAPによる治療効果の検討
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Description
<p>睡眠時無呼吸症候群(以下SAS)の胃食道逆流症(以下GERD)合併頻度を,QUEST問診票を用いて検討した.QUESTは4点以上をGERD合併ありと判断した.PSG(Polysomnography)検査を実施した84例中の73例にAHI(Apnea Hypopnea Index)≧5 (/hr) のSASを認めた.QUEST 4点以上が25例(34.2%)あり,GERD合併の有無で2群に分けたときAHI,脳波上の短時間覚醒指数(以下Arousal Index),BMIなどに有意差はなかった.AHI≧20かつQUEST≧4点の17例中,11例がCPAP治療を開始した.CPAP治療を開始した4週間後のQUEST得点は7例で無症状(0点)となった.残る4例はプロトンポンプ阻害薬(PPI)の内服を追加して,症状の消失が得られた.SASによる胸腔腹腔内圧較差開大をCPAP治療が改善して,胃酸逆流を抑制する機序が関与すると考える.SASには高頻度にGERDが合併することから積極的な問診と治療追加が望まれる.</p>
Journal
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- The Journal of the Japan Society for Respiratory Care and Rehabilitation
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The Journal of the Japan Society for Respiratory Care and Rehabilitation 14 (3), 491-495, 2005
The Japan Society for Respiratory Care and Rehabilitation
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Keywords
Details 詳細情報について
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- CRID
- 1390001205280094080
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- NII Article ID
- 130006199475
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- ISSN
- 21894760
- 18817319
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed