A case of a follicular dendritic cell sarcoma of the neck

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  • 頸部に発生した濾胞樹状細胞肉腫の1例

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Abstract

Follicular dendritic cell sarcoma (FDCS) is an uncommon neoplasm arising from follicular dendritic cells, which are antigen-presenting cells in lymphoid follicles.<br>A 65-year-old man had visited another hospital because of swelling of his left neck. Seven months later, a histopathological diagnosis of FDCS was made based on an incisional biopsy and so he was referred to our hospital for treatment.<br>The tumor was 45 mm in diameter, located in the accessory chain area and invading the skin over sternocleidmastoid muscle. A total excision with wide margins was performed and microscopically the surgical margin was free of tumor infiltration. He remains disease-free more than 2 years after surgery without chemotherapy or radiotherapy.<br>FDCS is considered to have a low to intermediate malignant potential, with a reported local recurrence rate of 23-43% and a distant metastasis rate of 21-24%. Clinical follow-up for local or distant relapse should be continued for years.

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