A retrospective study on parotid gland cancer

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  • Adachi Masahiro
    Department of Otolaryngology, University of Tsukuba Hospital
  • Nakayama Masahiro
    Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Tsukuba
  • Nishimura Bungo
    Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Tsukuba
  • Tanaka Shuho
    Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Tsukuba
  • Tabuchi Keiji
    Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Tsukuba
  • Wada Tetsuro
    Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Tsukuba
  • Hara Akira
    Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Tsukuba

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  • 当科における耳下腺癌の検討

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We retrospectively analyzed 35 patients with parotid gland cancer treated in our hospital between 2002 and 2015. There were 25 males and 10 females ranging in age from 31 to 84 years old with the median age of 65. Among the 35 patients, 3 patients （9％）, 5 patients （14％）, 6 patients （17％） and 21 patients （60％） were staged as Ⅰ, Ⅱ, Ⅲ and Ⅳ, respectively. The T stage was T1, T2, T3 and T4 in 3, 7, 7 and 18 patients, respectively. The N stage was N0, N1 and N2 in 20, 6 and 9 patients, respectively. Histopathologically, eleven types of malignancy were observed. The most common pathological type was acinic cell carcinoma in 6 patients. The overall 5-year survival rate of all 35 patients was 52.6％. The overall survival rates for Stage Ⅰ, Ⅱ, Ⅲ and Ⅳ, at 5 years were 100％, 75.0％, 33.3％ and 46.3％, respectively. Univariate analysis showed that significant prognostic factors for overall survival rate were cervical lymph node metastasis, grade, facial nerve resection, lymphatic/vascular invasion, and neural/perineural invasion. Patients with high-risk features are recommended to receive postoperative radiation therapy to improve the therapeutic outcomes.

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