Characteristics of induration occurring after intramuscular injection of haloperidol decanoate

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  • ハロペリドールデカン酸エステル注射液の筋肉内注射により発生する硬結の特徴

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<p>The present study was conducted to clarify the characteristics of induration caused by intramuscular injection of haloperidol decanoate, and to obtain information that could be relevant to nursing care methods for prevention of such induration.</p><p>We performed a case study and an animal experiment. In the animal experiment, we were able to reproduce the induration observed in patients.</p><p>Observations of tissue of induration revealed that haloperidol decanoate formed particles in muscle. In addition, an inflammatory reaction developed around the drug solution, and was persistent. It was thought that induration observed by the patient was a change of such a muscle tissue. When induration developed once, it did not disappear immediately.</p><p>Therefore, it is important to be made to disperse the drug solution and prevent induration.</p>

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  • Structure and Function

    Structure and Function 16 (2), 68-76, 2018

    Co-medical Research Society of Structure and Function

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