Thermal Ablation for Non-colorectal Liver Metastases
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- OTAO RYU
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- BEPPU TORU
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- ISIKO TAKATOSHI
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- HORINO KEI
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- KOMORI HIROYUKI
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- SUGIYAMA SHINICHI
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- MASUDA TOSHIRO
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- HAYASHI HIROMITSU
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- OKABE HIROHISA
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- IMSEUNG CHOI
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- HAYASHI NAOKO
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- WATANABE MASAYUKI
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- TAKAMORI HIROSHI
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
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- BABA HIDEO
- Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University
Bibliographic Information
- Other Title
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- 大腸癌以外の肝転移に対する熱凝固療法
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Abstract
Recent trends and therapeutic efforts to utilize thermal ablation for treating non-colorectal liver metastases are summarized. Thermal ablation, including microwave coagulation therapy and radiofrequency ablation were utilized for the treatment of liver metastases originating from neuroendocrine tumors, gastric cancer, breast cancer, thyroid cancer, pancreatobiliary cancer, etc. Hepatic resection is a first-line therapy for colorectal liver metastases, but not necessarily for non-colorectal liver metastases. In some patients with non-colorectal liver metastases, an important role of thermal ablation is to provide relief from symptoms and to reduce tumor size in combination with pharmacologic treatment. Local recurrence rates after thermal ablation were 6.3% for liver metastases from neuroendocrine tumors, and 14.7% for colorectal liver metastases. Of 3554 lesions treated, including 693 liver metastases, the mortality and morbidity rates were only 0.3% and 7.2%, respectively. Specific complications in using thermal ablation for non-colorectal liver metastases have never been reported. Excellent median survival times of 49 and 59 months were reported after thermal ablation for neuroendocrine and breast cancer liver metastases, respectively. Gastric cancer liver metastases are often accompanied with extrahepatic metastases and have a poor prognosis. However, if treated with hepatic arterial infusion chemotherapy followed by thermal ablation, the median survival time of 16.5 months was favorable. Thermal ablation has shown a therapeutic impact in the treatment of symptomatic liver-only metastases from neuroendocrine tumors, from a small number of metachronous tumors, a small number of gastric cancer liver metastases, especially when treated with hepatic arterial infusion chemotherapy, and in breast cancer liver metastases without visceral extrahepatic disease. Thermal ablation is a safe and effective procedure for selected non-colorectal liver metastases.
Journal
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- Thermal Medicine
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Thermal Medicine 25 (2), 35-41, 2009
Japanese Society for Thermal Medicine
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Details 詳細情報について
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- CRID
- 1390001205287818496
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- NII Article ID
- 130004504369
- 10025540058
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- NII Book ID
- AN10084762
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- ISSN
- 18823750
- 18822576
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- NDL BIB ID
- 10363938
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed