A bioinformatics strategy to produce a project structure of spiral development

DOI Web Site 2 Citations 7 References

Bibliographic Information

Other Title
  • 循環発展的なプロジェクト構造を生むバイオインフォマティクス戦略―創薬ターゲット遺伝子の網羅的機能解析―
  • ジュンカン ハッテンテキ ナ プロジェクト コウゾウ オ ウム バイオインフォマティクス センリャク ソウヤク ターゲット イデンシ ノ モウラテキ キノウ カイセキ
  • - - Comprehensive functional analysis of the drug design target genes -
  • － 創薬ターゲット遺伝子の網羅的機能解析 －

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Description

In the midst of the information flood of biological data, the role of the bioinformatics technology rises. This technology is expected to provide information to reduce the risk in the experiments and to help the designing of the experimental protocol. For this purpose, we mainly targeted a G protein coupling receptor (GPCR) and developed a computational pipeline which identifies these genes from genome sequences and performs their functional analyses. The applied results have been worked out into an integrated comprehensive functional analysis database (SEVENS). This core technology has become the trigger of collaborative researches, which continues today in a spiral evolutionary form. This flow is the dynamic form that continues advancing by the interaction between the research direction determined by three elements as a driving force and the direction of the life science fields progressing rapidly. The three elements are the core technique matured for a long term, the close cooperation with the experiment researcher, and the environment producing technical incubation.

Journal

  • Synthesiology

    Synthesiology 2 (4), 299-309, 2009

    National Institute of Advanced Industrial Science and Technology

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