Investigation of the Outbreak of Extended Spectrum Beta-Lactamase-Producing Klebsiella oxytoca
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- OKAMAE Tomoko
- Department of Infection Control and Prevention, Aichi Medical University Hospital Department of Infection Control Team, Aichi Medical University Hospital
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- KATO Yukiko
- Department of Infection Control and Prevention, Aichi Medical University Hospital Department of Infection Control Team, Aichi Medical University Hospital
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- YAMAGISHI Yuka
- Department of Infection Control and Prevention, Aichi Medical University Hospital Department of Infection Control Team, Aichi Medical University Hospital
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- MIKAMO Hiroshige
- Department of Infection Control Team, Aichi Medical University Hospital Department of Infection Control and Prevention, Aichi Medical University Hospital
Bibliographic Information
- Other Title
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- 基質拡張型β–ラクタマーゼ(extended-spectrum β–lactamase: ESBL)産生<i>Klebsiella oxytoca</i>のアウトブレイクの対応に関する検討
- キシツ カクチョウガタv-ラクタマーゼ(extended-spectrum v-lactamase : ESBL)サンセイ Klebsiella oxytoca ノ アウトブレイク ノ タイオウ ニ カンスル ケントウ
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Abstract
Since extended spectrum β-lactamase (ESBL) genes are located on a plasmid, transmission of ESBL genes might be possible beyond bacterial species. Therefore, resistant bacteria with ESBL genes might spread quickly and cause serious nosocomial infections. The outbreak of ESBL-producing Klebsiella oxytoca was detected in the neurosurgery ward of our hospital. Analysis using pulsed-field gel electrophoresis (PFGE) revealed horizontal transmission of only one strain. Since only reinforced hand hygiene was not effective to control the outbreak, we performed not only reinforced contact precautions but also education for medical staff and active screening for patients and medical staff, and isolation of patients. Such measures could lead to reduction of the outbreak. We considered that delay in aggressive intervention by the ICT would be associated with longer duration of the outbreak. We conclude that ICT intervention from the early stage and aggressive isolation strategy are necessary to control outbreaks of ESBL-producing bacteria.<br>
Journal
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- Japanese Journal of Infection Prevention and Control
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Japanese Journal of Infection Prevention and Control 27 (5), 315-322, 2012
Japanese Society for Infection Prevention and Control
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Details 詳細情報について
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- CRID
- 1390001205297372032
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- NII Article ID
- 130002575254
- 40019445079
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- NII Book ID
- AA12313188
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- ISSN
- 18832407
- 1882532X
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- NDL BIB ID
- 024006455
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed
