Evaluation of Disinfection Efficacy of Ethanol-based Preparation with 0.5 w/v% Chlorhexidine Gluconate and 0.2 w/v% Benzalkonium Chloride for Hand Antisepsis

  • NAKAGAWA Hiroo
    Department of Hospital Pharmacy, Nagasaki University Hospital of Medicine and Dentistry
  • MATSUDA Junichi
    Department of Laboratory Medicine, Nagasaki University Hospital of Medicine and Dentistry
  • YANAGIHARA Katsunori
    Department of Laboratory Medicine, Nagasaki University Hospital of Medicine and Dentistry
  • KITAHARA Takashi
    Department of Hospital Pharmacy, Nagasaki University Hospital of Medicine and Dentistry
  • SASAKI Hitoshi
    Department of Hospital Pharmacy, Nagasaki University Hospital of Medicine and Dentistry

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Other Title
  • 0.5w/v%グルコン酸クロルヘキシジンおよび0.2w/v%塩化ベンザルコニウム含有エタノール製剤の手指消毒効果に対する比較検討
  • 0 5w v グルコンサン クロルヘキシジン オヨビ 0 2w v エンカ ベンザルコニウム ガンユウ エタノール セイザイ ノ シュシ ショウドク コウカ ニ タイスル ヒカク ケントウ

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  Recently quick-drying antiseptics including 0.5 w/v% chlorhexidine gluconate/gel-alcohol (0.5%CHG-GA) have been sold in Japan. In this study, hand antiseptic effects and side effects of rough skin were compared with 0.2 w/v% benzalkonium chloride/liquid-alcohol (0.2%BAC-LA) which is the standard product. 0.5%CHG-GA had similar antiseptic effect to 0.2%BAC-LA immediately after hand antisepsis. 0.5%CHG-GA was superior to 0.2%BAC-LA during the 3 hours after hand antisepsis. There was no difference in the side effects of rough skin. Therefore, 0.5%CHG-GA is useful compared with 0.2%BAC-LA for prolonged hand antisepsis effects.<br>

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