The usefulness of platelet aggregation analysis before carotid artery stenting.

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  • ENOMOTO Yukiko
    Department of Neurosurgery, Graduate School of Medicine, Gifu University
  • YOSHIMURA Shinichi
    Department of Neurosurgery, Graduate School of Medicine, Gifu University
  • YAMADA Kiyofumi
    Department of Neurosurgery, Graduate School of Medicine, Gifu University
  • TAKAGI Toshinori
    Department of Neurosurgery, Graduate School of Medicine, Gifu University
  • IWAMA Toru
    Department of Neurosurgery, Graduate School of Medicine, Gifu University

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  • 頸部頸動脈ステント留置術における術前血小板凝集能測定の有用性

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Abstract

Objective: To determine whether platelet aggregation analysis is predictive of periprocedual ischemic or hemorrhagic events in patients undergoing carotid artery stenting (CAS), preoperative platelet aggregation in 18 patients scheduled for CAS was analyzed.<br>Methods: Blood samples were obtained from patients just before measurement of platelet aggregation with adenosine-diphosphoric acid (ADP) and collagen. All patients received diffusion-weighted image (DWI) on MRI at 1-3 days after the procedure.<br>Results: Maximum platelet aggregation rate was statistically higher in patients with ischemic events. In contrast, there was no difference in the positive rate of asymptomatic high intensity spots on DWI.<br>Conclusion: Preoperative platelet aggregation correlated with periprocedual ischemic events after CAS.

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