書誌事項
- タイトル別名
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- Recent Progress in the Synthetic Methodologies of Peptide Thioesters
- ペプチドチオエステル ゴウセイホウ ノ サイキン ノ シンテン
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説明
Investigations of biological processes by using peptide, protein, or its derivative are undoubtedly valuable. In this field, chemical synthesis of native or modified peptides/proteins is indispensable. Fragment condensation strategy, such as thioester method or native chemical ligation, is widely used for chemical synthesis of large peptides and proteins. C-Terminal peptide/protein thioesters have been used as building blocks for the fragment condensation strategy. Therefore, development of methodologies for preparing C-terminal peptide/protein thioesters is one of the most attracting theme in recent peptide/protein chemistry field. In this review, the methodologies for preparing C-terminal peptide/protein thioesters utilizing chemistry, biochemistry, or gene engineering are summarized.
収録刊行物
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- 有機合成化学協会誌
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有機合成化学協会誌 68 (9), 911-919, 2010
公益社団法人 有機合成化学協会
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詳細情報 詳細情報について
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- CRID
- 1390001205312881408
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- NII論文ID
- 10026870593
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- NII書誌ID
- AN0024521X
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- ISSN
- 18836526
- 00379980
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- NDL書誌ID
- 10821083
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可