書誌事項
- タイトル別名
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- Tissue Engineering using Nanofiber
- ナノファイバー オ リヨウ シタ サイセイ イリョウ
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Electrospinning (ESP) is a powerful method to produce polymer fibers with nanometer-scale diameters. This article describes the application of nanofiber using polylactic acid for tissue engineering. The diameter and surface structure of nanofiber were easily controlled by the conditions of the ESP.<BR>The influences of fiber diameter on cell adhesion and proliferation were examined by culutivating NIH 3 T 3 (fibroblast cell) on nanofibrous meshes. As a result, it was proved that the control of cell adhesion and proliferation was accomplished with changing a fiber diamter.<BR>We succeeded in the production of a new biodegradable and elastic material which was a combined nanofiber with cross-linked elastin. The obtained tubular material showed excellent mechanical property equal to blood vessel and peripheral nerve tissue. Finally, the regeneration of peripheral nerve axon was observed by transplantation using rat model with sciatic trauma.
収録刊行物
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- 有機合成化学協会誌
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有機合成化学協会誌 62 (5), 514-519, 2004
公益社団法人 有機合成化学協会
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詳細情報 詳細情報について
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- CRID
- 1390001205313126528
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- NII論文ID
- 10012930210
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- NII書誌ID
- AN0024521X
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- COI
- 1:CAS:528:DC%2BD2cXktVKgtb8%3D
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- ISSN
- 18836526
- 00379980
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- NDL書誌ID
- 6946162
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可