クセノプス (<I>Xenopus laevis</I>) と食用ガエル (<I>Rana catesbiana</I>) の血球, 胃粘膜水溶性画分の血液型活性について

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  • ON BLOOD GROUP ACTIVITIES OF ERYTHROCYTES AND WATER-SOLUBLE FRACTIONS OF GASTRIC MUCOSA IN <I>XENOPUS LAEVIS AND RANA CAT ESBIANA</I>.
  • クセノプス Xenopus laevis ノ ショクヨウ ガエル Rana catesbiana ノ ケッキュウ , イ ネンマク スイヨウセイ カクブン ノ ケツエキガタ カッセイ ニ ツイテ

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1. The absorption test of group-specific agglutinins was used to identify blood-group ABO activities of the erythrocytes and water-soluble fractions obtained from the pepsin digests of gastric mucosa in toads, Xenopus laevis and frogs, Rana catesbiana, and in addition, the group-specific precipitation reaction was used for these water-soluble fractions.<BR>2. The erythrocytes of the toads do not contain any substances on blood-goup ABO system, whereas that of the frogs contain blood-group B substance.<BR>3. It was confirmed that the toads have high AH antigenicity, and the frogs have high BH antigenicity with xeak A activity so far as the water-soluble fractions is concerned. The evidence that rabbits produce high titre of anti-A antibody after injection of the formcr's preparation and high titre of anti-B antibody after injection of the latter's one shows these water-soluble fractions to be an antigenic substance but not to be a hapten-like substance.<BR>4. Treatment of the water-soluble fractions by four kinds of glycosidases elucidated that A antigenicity in the toads and B antigenicity in the frogs are determined by α-N-acetyl-D-galactosaminyl and α-D-galactosyl residues, respectively, accompanying low level of serological changes from A to H and from B to H.

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