AN AUTOPSY CASE OF PERICARDIAL MESOTHELIOMA ASSOCIATED WITH SEVERE HEMOPERICARDIUM

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  • Hoshi Shoji
    Department of Pathology, Internal Medicine and Surgery, Totigi National Hospital
  • Ato Norio
    Department of Pathology, Internal Medicine and Surgery, Totigi National Hospital
  • Handa Yoshitsugu
    Department of Pathology, Internal Medicine and Surgery, Totigi National Hospital

Bibliographic Information

Other Title
  • 著明な心嚢血腫を伴なった心嚢中皮腫の一剖検例
  • チョメイ ナ シンノウ ケッシュ オ トモナッタ シンノウ チュウヒ シュ ノ イチ ボウケンレイ

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Description

An autopsy case of primary mesothelioma of the pericardium was reported. The case was male Japanese, 53 years old.<BR>He was admitted to this hospital with chief complaints of tightnese sensation in the chest, he had a large heart shadow and numerous, tumor cells were found in the hemorrhagic pericardial fluid.<BR>However, tumor formation was not discovered anywhere by clinical examination.<BR>At autopsy, left lung was displaced laterally and posteriorly by greatly enlarged pericardial sac. The pericardial cavities contained hemorrhagic fluid and all pericardial surfaces were studded with gray and brown nodules, and so the parietal pericardium was thickened. There were no metastases in other organs.<BR>Microscopic examination and multiple sections revealed tumor tissue invasing visceral and parietal pericardium.<BR>The tumor was composed of two main cell types, epithelial and spindle. Cells were arranged in a fibrous tissue with a small amount of interspersed hyaline matrix. In most areas the tumor was papillary or formed clefts while elsewhere sheets of spindle cells were prominent.

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