Effect of Age on Lipid Metabolism in Epididymal Adipose Tissue The Correlation between Cell Size and Metabolic Alterations

DOI Web Site
  • MIZUNUMA Toshimi
    Department of Nutrition, School of Medicine, Tokushima University
  • SATO Fumiyo
    Department of Nutrition, School of Medicine, Tokushima University
  • KISHINO Yasuo
    Department of Nutrition, School of Medicine, Tokushima University
  • OKUDA Hiromichi
    Department of Biochemistry, School of Medicine, Ehime University

Bibliographic Information

Other Title
  • 加齢にともなう脂質代謝の変動についてとくに脂肪細胞の大きさとの関係を中心に
  • カレイ ニ トモナウ シシツ タイシャ ノ ヘンドウ ニ ツイテ トクニ シボ

Search this article

Description

Experiments were carried out to elucidate the mechanism of triglyceride accumulation in epididymal adipose tissue of young and aged rats, with special reference to fat mobilization and deposition. In aged rats, the weight of the epididymal adipose tissue was 2, 000 per cent that of young rats, while adrenaline-induced lipolysis and lipase activity of the adipose tissue were 600 and 1, 600 per cent those of young rats, respectively. These results suggest that deposition of fat far exceeds fat mobilizing activity in the adipose tissue of aged rats. It was found that triglyceride synthesis from glucose and palmitate was higher in the adipose tissue of aged rats. Therefore, it is suggested that triglyceride deposition in the adipose tissue of aged rats may not be due to decrease in fat mobilization but to increase in triglyceride synthesis.

Journal

  • Eiyo To Shokuryo

    Eiyo To Shokuryo 30 (1), 7-13, 1977

    JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE

Details 詳細情報について

Report a problem

Back to top