研究ノートカルシウム不足による白ネズミの胃粘膜変化について

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書誌事項

タイトル別名
  • Changes of the Rat Stomach Mucosa Induced by Calcium Deficiency
  • カルシウム フソク ニヨル ハク ネズミ ノ イ ネンマク ヘンカ ニ ツイテ

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説明

The present report describes an experiment to study the relationship between etiological factor (s) in allimentary tracts, especially stomach mucosa, and nutritional deficiency such as calcium deficiency.<BR>Basal diet resembled to a typical food ingredient in Japan was composed of mostly powdered polished rice, defatted soybean, soybean oil, salt mixture and vitamin mixture.<BR>Groups investigated were fed for 8 weeks with each test diet such as (I) low Ca, normal vitamin D, low vitamin A, (II) normal Ca, low vitamin D, low vitamin A, (III) low Ca, low vitamin D, low vitamin A, (IV) normal Ca, low vitamin D, normal vitamin A, (V) low Ca, low vitamin D, normal vitamin A, respectively.<BR>On the late period of the experiment, urine was collected to examine Ca and P excretion in such a condition.<BR>After animals were sacrificed, chemical analyses on serum, vitamins (liver vitamin A, renal thiamine and riboflavin) and skeltal matter were determined to judge the physiological condition of the animal, and stomach mucosa was histologically examined.<BR>Results indicated<BR>1) P excretion was greatly increased by Ca deficiency whereas Ca retention was rather even regerdless to Ca intake.<BR>2) Vitamin D considerably moderated mineral metabolism disorder induced by Ca deficiency, as judged from chemical analyses.<BR>3) Histological findings denoted Ca deficient diet might be a potential inducer of degenerative changes in rat stomach mucosa unless vitamin D was sufficiently administered.

収録刊行物

  • 栄養と食糧

    栄養と食糧 30 (1), 47-51, 1977

    公益社団法人 日本栄養・食糧学会

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