ラット尿より分離した食欲抑制物質 (FMS-1A) について

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書誌事項

タイトル別名
  • Anorexigenic Substance (FMS-1A) Extracted from Rat Urine
  • ラット ニョウ ヨリ ブンリシタ ショクヨク ヨクセイ ブッシツ FMS 1A

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抄録

Anorexigenic activity of FMS-1A extracted from rat urine by the method of Stevenson et al. was examined. The significant reduction in body weight and anorexigenic effect on food and water intake were followed by the intraperitoneal injection of FMS-1A into rats. It was demonstrated that FMS-1A was a substance related to protein, and its anorexigenic activity remained after standing at room temperature for 10 days. Then the collected rat urine was concentrated by ultrafiltration method and fractionated. A fraction having molecular weight more than 5, 000 also showed the anorexigenic activity. This result suggests that anorexigenic substance is present in normal rat urine, but it gets no activity by treatment of alcohol and/or benzoic acid.

収録刊行物

  • 栄養と食糧

    栄養と食糧 30 (5), 303-306, 1977

    公益社団法人 日本栄養・食糧学会

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