The Effects of the Dietary α-Tocopherol and Different Sugars on Liver and Plasma Lipids in Rats

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  • CHO Shuji
    Department of Home Life Science, Fukuoka Women's University
  • YAMAMOTO Kyosuke
    The Third Department of Internal Medicine, Kyushu University School of Medicine
  • IDE Takashi
    Department of Food Science and Technology, Kyushu University School of Agriculture
  • SUGANO Michihiro
    Department of Food Science and Technology, Kyushu University School of Agriculture

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Other Title
  • α-トコフェロールのレベルならびに糖質の種類を異にした食餌を与えたラットの肝臓, 血漿の脂質成分
  • アルファ トコフェロール ノ レベル ナラビニ トウシツ ノ シュルイ オ イ

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Description

The present study is focussed on examining the influences of dietary tocopherol on plasma and liver lipids in rats, in an appropriate combination with different dietary sugars (glucose, sucrose or fructose). Male and female rats of Wistar strain were fed diets ad libitum for 2 weeks. dl-α-Tocopheryl acetate was added to the diets in three different levels (A, B and C groups) depending on the conditions of the experiments.<BR>(1) The concentrations of plasma cholesterol and triglyceride were not necessarily reduced by increasing tocopherol levels in the diets. In some groups of rats fed fructose, the accumulation of liver triglyceride was essentially prevented by the administration of increasing levels of tocopherol.<BR>(2) Tocopherol supplementation caused, in most cases of the experiments using sucrose or fructose as dietary sugars, marked changes in percentage of hepatic arachidonic acid compared with those of other polyunsaturated fatty acids.<BR>(3) The alterations of plasma and liver lipids by dietary tocopherol were most remarkable in rats fed fructose.<BR>(4) From the results of these experiments, it is apparent that the effects of tocopherol on plasma and liver lipids differ with the sources of dietary sugars and other constituents and/or body weights and sexes of the experimental animals.

Journal

  • Eiyo To Shokuryo

    Eiyo To Shokuryo 30 (5), 275-281, 1977

    JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE

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