いわゆる「白ろう病」の発生素因に関する研究

Plethysmography was performed 5 times at an hour intervals at a room temperature of 20°C with 29 healthy subjects and 10 male forestry workers who had history of Raynaud's phenomenon, but had not developed it for the last 6 months or more (here after referred to as Raynaud subjects).<BR>The chief findings were as follows :<BR>1) Plethysmograms from 29 healthy subjects revealed that in 4 cases (14%) (designated as group A), wave height was great, with change occurring always at the parts of great height, that in 5 cases (17%) (designated as group C), wave height was small, with change occurring always at the parts of small height, and that in the remaining 20 cases (69%) (designated as group B), the finding was intermediate between the above two. Of the 10 Raynaud subjects, however, 8 cases (80%) belonged to group C and the remaining 2 cases to goup B.<BR>2) To seek the effects of age and occupation on plethysmogram, the wave recording was made twice with each of the 5 healthy forestry workers, and the findings were near to those of the Raynaud subjects. It was thus found that age and occupation exert great effect on plethysmogram.<BR>3) With the healthy subjects, plethysmogram was catacrotic wave in the highest percentage (63. 4%), and sclerotic wave was never seen. With the Raynaud subjects, however, wave form was catacrotic (24%), sclerotic (54%), platean (12%) and arch wave (10%), thus showing significant difference from the healthy subjects. The 5 healthy workers showed catacrotic wave (30%), transitional type from anacrotic to sclerotic wave (30%), and anacrotic wave (40%), being thus intermediate between the above two groups. Of the healthy subjects, 62.1% showd temporal change in the wave form, while only 30% of the Raynaud subjects exhibited the change.<BR>4) The mean up-stoke time ranged 0.13-0.16 sec. with the healthy subjects, and 0.23-0.28 sec. with the Raynaud subjects, thus being prolonged in the latter. With the healthy workers it ranged 0.190.24sec., thus being intermediate.<BR>5) As for change in the base line with shift in the position of the examinee, no definite direction was indicated.<BR>6) With the healthy subjects, there was relationship between classifications by wave height of plethysmograma and by skin temperature, but such was not observed with the Raynaud subjects. No relation was observed between the former and the classification by color or humidity of the skin.<BR>7) Some of the healthy subjects showed similar wave height to that of the Raynaud subjects, indicating the possibility of a predisposition for Raynaud's disease.