Production of Fatty Acids from 1-Propanol in <I>Pseudomonas</I> sp

  • YAGI Hisaaki
    Biological Chemistry Division, National Chemical Laboratory for Industry
  • YOKOCHI Toshihiro
    Biological Chemistry Division, National Chemical Laboratory for Industry
  • KAMISAKA Yasushi
    Biological Chemistry Division, National Chemical Laboratory for Industry
  • YAMAOKA Masakazu
    Biological Chemistry Division, National Chemical Laboratory for Industry
  • NAKAHARA Toro
    Biological Chemistry Division, National Chemical Laboratory for Industry
  • SUZUKI Osamu
    Biological Chemistry Division, National Chemical Laboratory for Industry

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Other Title
  • <I>Pseudomonas</I> sp における1-プロパノールからの脂肪酸の生産
  • Pseudomonas sp ニ オケル 1 プロパノール カラ ノ シボウサ

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Description

Pseudomonas sp (ATCC 12085) grown in a medium containing 1-propanol produced pentadecanoic (C15), heptadecanoic (C17), heptadecenoic (C17 : 1), and methyleneheptadecanoic acids (C18cyc), a cyclopropane fatty acid. The ratio of these fatty acids except for heptadecenoic acid to all fatty acids increased with the growth of Pseudomonas. Maximum concentrations of these fatty acids were obtained at 0.5 % 1-propanol. The fatty acids were also produced in the presence of sodium propionate instead of 1-propanol. The production of odd-numbered fatty acids and methylene-heptadecanoic acid by Pseudomonas sp can be explained based on the intermediary propionyl-CoA from 1-propanol and propionicacid.

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