有機結晶のキラリティーを利用した不斉合成法の開発

DOI Web Site Web Site 参考文献66件

書誌事項

タイトル別名
  • Asymmetric Synthesis Using Crystal Chirality
  • ユウキ ケッショウ ノ キラリティー オ リヨウ シタ フセイ ゴウセイホウ ノ カイハツ

この論文をさがす

抄録

<p>Asymmetric synthesis from achiral starting materials using only crystal chirality under absolutely achiral conditions-that is, absolute asymmetric synthesis-has been investigated by many methods, including solid-state photochemical reactions, asymmetric reactions using frozen chirality, and dynamic crystallization (total spontaneous resolution). Dynamic crystallization using racemic conglomerate crystals involved that an enantiomerically enriched solid state could be achieved through crystallization from a solution in which chiral molecules could rapidly racemize. Many such examples resulted in total optical resolution by deracemization, selectively leading to single-handed molecules. Furthermore, a combined methodology for generating a chiral center from achiral materials, involving dynamic crystallization or attrition-enhanced deracemization, was recently developed. These examples demonstrate the high potential of this new category of absolute asymmetric synthesis.</p>

収録刊行物

参考文献 (66)*注記

もっと見る

関連プロジェクト

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ