書誌事項
- タイトル別名
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- Unique Reactivity of Pyranosides with 2,3-<i>trans</i> Carbamate Group; Renaissance of Endocyclic Cleavage Reaction
- 2,3-transカーバメート基を持つ糖構造の特異な反応性 : 糖化学におけるエンド開裂反応の再発見
- 2,3-trans カーバメートキ オ モツ トウ コウゾウ ノ トクイ ナ ハンノウセイ : トウカガク ニ オケル エンドカイレツハンノウ ノ サイハッケン
- Unique Reactivity of Pyranosides with 2,3-trans Carbamate Group; Renaissance of Endocyclic Cleavage Reaction
この論文をさがす
抄録
1,2-cis amino glycosides are often found in biologically active oligosaccharides. For the stereoselective formation of 1,2-cis aminoglycosides, glycosyl donors with 2,3-trans carbamate group were developed. The first synthesis of anti-Helicobacter pylori oligosaccharide was achieved by using the novel glycosyl donor in an effective manner. Furthermore, the pyranosides with 2,3-trans carbamate groups were found to undergo endocyclic cleavage reactions, which are rarely found in pyranosides. The endocyclic cleavage reaction was confirmed both from experimental and computational approaches.<BR>As an additional example of cooperative work of experimental and computational chemistry, understanding of the solvent effect in glycosylation reactions was also described.
収録刊行物
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- 有機合成化学協会誌
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有機合成化学協会誌 71 (6), 616-624, 2013
公益社団法人 有機合成化学協会
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詳細情報 詳細情報について
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- CRID
- 1390001205340679296
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- NII論文ID
- 10031178159
- 130003373306
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- NII書誌ID
- AN0024521X
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- COI
- 1:CAS:528:DC%2BC3sXpsVGis7c%3D
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- ISSN
- 18836526
- 00379980
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- NDL書誌ID
- 024687292
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
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- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可