Development of Synthetic Methodologies for Heterocycles Using Diene-transmissive Hetero-Diels-Alder Reaction
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- Saito Takao
- Department of Chemistry, Faculty of Science, Tokyo University of Science
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- Kobayashi Satoru
- Central Pharmaceutical Research Institute, Japan Tabacco Inc.
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- Otani Takashi
- Course of Chemical Engineering, National Institute of Technology, Anan College
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- Kutsumura Noriki
- International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba
Bibliographic Information
- Other Title
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- ジエン伝達ヘテロDiels-Alder反応を利用した複素環合成法の開発
- ジエン デンタツ ヘテロ Diels-Alder ハンノウ オ リヨウ シタ フクソカン ゴウセイホウ ノ カイハツ
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Description
<p>The diene-transmissive hetero-Diels-Alder reaction (DTHDA reaction) is a special case of the DTDA reaction in which one or more heteroatoms are contained within either a cross-conjugated triene/polyene (heterodendralene) π-system, a dienophile π-system or both. Therefore, the DTHDA protocol is an efficient and attractive method for the stereoselective synthesis of a variety of heterocyclic systems. Merits and potential of the DTHDA methodology for heterocyclic synthesis can be widely extended by structural variations and complexity of both diene and dienophile; the kind, numbers, and positions of heteroatoms contained in either the cross-conjugated triene/polyene ([3/n] heterodendralene) or the dienophile framework, as well as the inter- or intramolecular cycloaddition mode, and its predictable regio- and stereoselectivities. In this paper, we introduce the synthesis of a variety of heterocycles using the DTHDA reaction with a focus on our research.</p>
Journal
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- Journal of Synthetic Organic Chemistry, Japan
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Journal of Synthetic Organic Chemistry, Japan 74 (8), 803-813, 2016
The Society of Synthetic Organic Chemistry, Japan
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Keywords
Details 詳細情報について
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- CRID
- 1390001205341224448
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- NII Article ID
- 130005261223
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- NII Book ID
- AN0024521X
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- ISSN
- 18836526
- 00379980
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- NDL BIB ID
- 027552817
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed