Donor-Acceptor Bifunctional Molecular Catalyst: Its Development, Application, and Analysis

Kitamura Masato, Tanaka Shinji, Yoshimura Masahiro

doi:10.5059/yukigoseikyokaishi.73.690

Bibliographic Information

Other Title

分子触媒の開発・応用・機構解明—ドナー・アクセプター2官能性触媒の展開—
分子触媒の開発・応用・機構解明 : ドナー・アクセプター2官能性触媒の展開
ブンシショクバイノカイハツ・オウヨウ・キコウカイメイ : ドナー・アクセプター 2 カンノウセイショクバイノテンカイ

Search this article

Abstract

De novo development of molecular catalyst (MC) for a targeted ideal reaction is challenging and requires deep understanding of chemistry. Irrespective of the how and why for the finding of high performance MC realizing high reactivity, turnover frequency, selectivity, and productivity, the mechanism should be pursued because it offers a great source of creativity. A detailed mechanistic study of Oguni asymmetric reaction catalyzed by DAIB-Zn complex (DAIB: 3-exo-dimethylaminoisoborneol) has established a new leading concept, that is “Donor-Acceptor Bifunctional Catalyst (DACat),” for the design of a MC. The concept has been categorized into four by two parameters: i) intramolecular (Intramol) or intermolecular (Intermol) and ii) metathesis (M)- or redox (R)-type reaction. The four concepts have realized a new type of MCs including asymmetric hydrogenation of ketones, allyloxy bond cleaving reaction, and asymmetric dehydrative allylation. This account overviews the results obtained in our group.

Journal

Journal of Synthetic Organic Chemistry, Japan

Journal of Synthetic Organic Chemistry, Japan 73 (7), 690-700, 2015

The Society of Synthetic Organic Chemistry, Japan

Keywords

Details 詳細情報について

Export