書誌事項
- タイトル別名
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- On the Aotion of β-Indolylethylamine
- On the Aotion of ^|^beta;-Indolylethylamine
説明
The action of p-indolylethylamine varies in several respects according to the reports of different workers, and these variations seem to be due to the difference in purity of the base employed by them. In order to determine the action of the base the authors made experiments on rabbits by using geburamine, the acetate of p-indolylethylamine, which was proved to be chemically pure, and the results obtained are as follows : -<BR>The base first stimulates the central nervous system, giving rise to acceleration of the respiration and convulsions, and later paralyzes it, arresting the voluntary and respiratory movements. In small doses it causes a slight rise in the blood-pressure due to the increase in the rate and amplitude of the heart beats and constriction of the vessels ; while in large doses a fall by depressing the heart and dilating the vessels. It increases the tone and movements of the uterus through its action on the contractile elements, but in large doses decreases them. Moreover, it has an action to paralyze the augmentary sympathetic ends of the uterus, which is usually overshadowed by the muscular action.
収録刊行物
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- 日本藥物學雜誌
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日本藥物學雜誌 1 (0), 341-351,en16, 1925
公益社団法人 日本薬理学会
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詳細情報 詳細情報について
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- CRID
- 1390001205354379008
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- NII論文ID
- 130003727176
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- ISSN
- 2185307X
- 03694461
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
